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Radiology.Academy.Sk

Thyroroxicosis scintigraphy

Thyroroxicosis scintigraphy

I-131 is produced in nuclear reactor (too many neutrons), beta minus decay. 364keV, half-life 8d
I-123 is preferred agent now, produced in cyclotron (too many protons), electron capture, gamma emission, 159keV, half-life 13.2h, 18x more expensive than 1-131

Iodine 20% extrcate dby thyroid, 80% into urine

Entrapment
Organification

Radioiodine I-131, I-123
Tc-99m Pertechnate, generator produced, 140keV photopeak, short half-life, lowest dose, IV, not organified
F-18G

RAIU - RadioActive Iodine Uptake

Graves d: most common cause of thyrotoxicosis, TSAb (Thyroid stimulating Ab), 24h RAIU 80%; Marine-Lenhart: w/ cold nodules (nl tissue)
TMNG: Toxic multinodular goite, patchy looking thyroid gland
Toxic adenoma: autonomous nodule, always on,

de Quervain Thyroiditis: thyrotoxicosisi due to viral damage to the gland, low uptake, initially thytotoxic then hypothyroid

Amiodarone is #1 cause of med-induced thyrotoxicosis

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